a tool for identifying drug-targetable redox-active disulphides

Chymosin

Intramolecular

Cysteine 105 and cysteine 110

A redox-regulated disulphide may form within Chymosin between cysteines 105 and 110 (47 and 52 respectively in this structure).

Details

Redox score ?

88

PDB code

Structure name

the three-dimensional structure of recombinant bovine chymosin at 2

Structure deposition date

1989-10-12

Thiol separation (Å)

2

Half-sphere exposure sum ?

63

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

105

Residue number B

110

Peptide name

Chymosin

Ligandability

Cysteine 105 of Chymosin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 110 of Chymosin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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